Oral Sodium Loading in Normal Individuals

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Oral sodium loading in normal individuals.

At the commencement of the Peru Burn Project (1) in 1951, great apprehension was aroused in many by the use of large quantities of isotonic saline solutions 6 in the treatment of burned patients, for it was believed that such therapy in individuals retaining sodium due to the stress reaction would overload the circulation and lead to death in pulmonary edema. The reason for this fear was based ...

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Contrasting endocrine responses to acute oral compared with intravenous sodium loading in normal humans.

There is evidence in animals and in humans for accelerated natriuresis after oral compared with intravenous sodium loading. To assess the role of atrial natriuretic peptide (ANP) as a contributory mechanism, we compared the hormonal responses to an intravenous sodium load and to the same sodium load taken orally in three separate groups of healthy subjects in balance on low, normal, or high sod...

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The Frequency of Candida Albicans in the Oral Cavity of Patients withMajor Thalassemia and Normal Individuals

Abstract Background and objectives: Candida albicans is a normal flora in skin and mucosa and is not pathogen in normal individuals.The main defence against yeasts ,particulary Candida, is phagocytes, but phagocytesis and opsonization are reduced in thalassemia . the aim of this study was the determination of the frequency of Candida albicans and its species in the oral cavity of patients with ...

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Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading.

BACKGROUND Studies have shown that the rise in intracellular ionized calcium, [Ca2+]i, in hypoxic myocardium is driven by an increase in sodium, [Na+]i, but the source of Na+ is not known. METHODS AND RESULTS Inhibitors of the voltage-gated Na+ channel were used to investigate the effect of Na+ channel blockade on hypoxic Na+ loading, Na(+)-dependent Ca2+ loading, and reoxygenation hypercontr...

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The effect of chronic sodium loading and sodium restriction on plasma prostaglandin A, E, and F concentrations in normal humans.

It has been suggested that prostaglandins may be involved in the control of sodium homeostasis. Prostaglandin A and prostaglandin E have been shown to increase renal blood flow and urinary sodium excretion and prostaglandin A has been shown to stimulate aldosterone release. The purpose of this study was to determine the effect of chronic sodium loading and sodium restriction on plasma prostagla...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1957

ISSN: 0021-9738

DOI: 10.1172/jci103425